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Gα13 Mediates a Signal That Is Essential for Proliferation and Survival of Thymocyte Progenitors
G protein signaling via the Gα12 family (Gα12 and Gα13) has not been well studied in T cells. To investigate whether Gα12 and Gα13 are involved in thymopoiesis, we expressed the regulator of G protein signaling domain of p115RhoGEF to inhibit Gα12 and Gα13 during thymopoiesis. Fetal thymus organ cul...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2211919/ https://ncbi.nlm.nih.gov/pubmed/15534370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040944 |
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