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Gα13 Mediates a Signal That Is Essential for Proliferation and Survival of Thymocyte Progenitors

G protein signaling via the Gα12 family (Gα12 and Gα13) has not been well studied in T cells. To investigate whether Gα12 and Gα13 are involved in thymopoiesis, we expressed the regulator of G protein signaling domain of p115RhoGEF to inhibit Gα12 and Gα13 during thymopoiesis. Fetal thymus organ cul...

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Hlavní autoři: McNeil Coffield, V., Helms, Whitney S., Jiang, Qi, Su, Lishan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211919/
https://ncbi.nlm.nih.gov/pubmed/15534370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040944
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