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Phosphorylation Events in the Multiple Gene Regulator of Group A Streptococcus Significantly Influence Global Gene Expression and Virulence

Whole-genome sequencing analysis of ∼800 strains of group A Streptococcus (GAS) found that the gene encoding the multiple virulence gene regulator of GAS (mga) is highly polymorphic in serotype M59 strains but not in strains of other serotypes. To help understand the molecular mechanism of gene regu...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Sanson, Misu, Makthal, Nishanth, Gavagan, Maire, Cantu, Concepcion, Olsen, Randall J., Musser, James M., Kumaraswami, Muthiah
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432744/
https://ncbi.nlm.nih.gov/pubmed/25824840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.03023-14
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