Phosphorylation Events in the Multiple Gene Regulator of Group A Streptococcus Significantly Influence Global Gene Expression and Virulence

Whole-genome sequencing analysis of ∼800 strains of group A Streptococcus (GAS) found that the gene encoding the multiple virulence gene regulator of GAS (mga) is highly polymorphic in serotype M59 strains but not in strains of other serotypes. To help understand the molecular mechanism of gene regu...

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Vydáno v:Infect Immun
Hlavní autoři: Sanson, Misu, Makthal, Nishanth, Gavagan, Maire, Cantu, Concepcion, Olsen, Randall J., Musser, James M., Kumaraswami, Muthiah
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432744/
https://ncbi.nlm.nih.gov/pubmed/25824840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.03023-14
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