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Structural and functional analysis of RopB: a major virulence regulator in S treptococcus pyogenes

Group A Streptococcus (GAS) is an exclusive human pathogen that causes significant disease burden. Global regulator RopB of GAS controls the expression of several major virulence factors including secreted protease SpeB during high cell density. However, the molecular mechanism for RopB‐dependent sp...

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Bibliografiske detaljer
Udgivet i:Mol Microbiol
Main Authors: Makthal, Nishanth, Gavagan, Maire, Do, Hackwon, Olsen, Randall J., Musser, James M., Kumaraswami, Muthiah
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794775/
https://ncbi.nlm.nih.gov/pubmed/26714274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13294
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