An N-Terminal Signal Peptide Of Vfr Protein Negatively Influences RopB-Dependent SpeB Expression and Attenuates Virulence in Streptococcus pyogenes

Streptococcal pyrogenic exotoxin B (SpeB) is an extracellular cysteine protease that is a critical virulence factor made by the major human pathogen group A Streptococcus (GAS). speB expression is dependent on the regulator of proteinase B (RopB) and is upregulated with increasing cell density and d...

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Bibliografiska uppgifter
I publikationen:Mol Microbiol
Huvudupphovsmän: Shelburne, Samuel A., Olsen, Randall J., Makthal, Nishanth, Brown, Nicholas G., Sahasrabhojane, Pranoti, Watkins, Ebru M., Palzkill, Timothy, Musser, James M., Kumaraswami, Muthiah
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571278/
https://ncbi.nlm.nih.gov/pubmed/22040048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07902.x
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