Iron Efflux by PmtA Is Critical for Oxidative Stress Resistance and Contributes Significantly to Group A Streptococcus Virulence

Group A Streptococcus (GAS) is a human-only pathogen that causes a spectrum of disease conditions. Given its survival in inflamed lesions, the ability to sense and overcome oxidative stress is critical for GAS pathogenesis. PerR senses oxidative stress and coordinates the regulation of genes involve...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: VanderWal, Arica R., Makthal, Nishanth, Pinochet-Barros, Azul, Helmann, John D., Olsen, Randall J., Kumaraswami, Muthiah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442632/
https://ncbi.nlm.nih.gov/pubmed/28348051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00091-17
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