Iron Efflux by PmtA Is Critical for Oxidative Stress Resistance and Contributes Significantly to Group A Streptococcus Virulence

Group A Streptococcus (GAS) is a human-only pathogen that causes a spectrum of disease conditions. Given its survival in inflamed lesions, the ability to sense and overcome oxidative stress is critical for GAS pathogenesis. PerR senses oxidative stress and coordinates the regulation of genes involve...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Infect Immun
Prif Awduron: VanderWal, Arica R., Makthal, Nishanth, Pinochet-Barros, Azul, Helmann, John D., Olsen, Randall J., Kumaraswami, Muthiah
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2017
Pynciau:
Molecular Pathogenesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442632/
https://ncbi.nlm.nih.gov/pubmed/28348051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00091-17
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