Crystal Structure of Peroxide Stress Regulator from Streptococcus pyogenes Provides Functional Insights into the Mechanism of Oxidative Stress Sensing

Regulation of oxidative stress responses by the peroxide stress regulator (PerR) is critical for the in vivo fitness and virulence of group A Streptococcus. To elucidate the molecular mechanism of DNA binding, peroxide sensing, and gene regulation by PerR, we performed biochemical and structural cha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Makthal, Nishanth, Rastegari, Sheila, Sanson, Misu, Ma, Zhen, Olsen, Randall J., Helmann, John D., Musser, James M., Kumaraswami, Muthiah
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2013
Pynciau:
Protein Structure and Folding
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689973/
https://ncbi.nlm.nih.gov/pubmed/23645680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.456590
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