Crystal Structure of Peroxide Stress Regulator from Streptococcus pyogenes Provides Functional Insights into the Mechanism of Oxidative Stress Sensing

Regulation of oxidative stress responses by the peroxide stress regulator (PerR) is critical for the in vivo fitness and virulence of group A Streptococcus. To elucidate the molecular mechanism of DNA binding, peroxide sensing, and gene regulation by PerR, we performed biochemical and structural cha...

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Hlavní autoři: Makthal, Nishanth, Rastegari, Sheila, Sanson, Misu, Ma, Zhen, Olsen, Randall J., Helmann, John D., Musser, James M., Kumaraswami, Muthiah
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689973/
https://ncbi.nlm.nih.gov/pubmed/23645680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.456590
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