Crystal Structure of Peroxide Stress Regulator from Streptococcus pyogenes Provides Functional Insights into the Mechanism of Oxidative Stress Sensing

Regulation of oxidative stress responses by the peroxide stress regulator (PerR) is critical for the in vivo fitness and virulence of group A Streptococcus. To elucidate the molecular mechanism of DNA binding, peroxide sensing, and gene regulation by PerR, we performed biochemical and structural cha...

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Dades bibliogràfiques
Autors principals: Makthal, Nishanth, Rastegari, Sheila, Sanson, Misu, Ma, Zhen, Olsen, Randall J., Helmann, John D., Musser, James M., Kumaraswami, Muthiah
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689973/
https://ncbi.nlm.nih.gov/pubmed/23645680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.456590
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