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Mechanisms of Stage-Transcending Protection Following Immunization of Mice with Late Liver Stage-Arresting Genetically Attenuated Malaria Parasites

Malaria, caused by Plasmodium parasite infection, continues to be one of the leading causes of worldwide morbidity and mortality. Development of an effective vaccine has been encumbered by the complex life cycle of the parasite that has distinct pre-erythrocytic and erythrocytic stages of infection...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Sack, Brandon K., Keitany, Gladys J., Vaughan, Ashley M., Miller, Jessica L., Wang, Ruobing, Kappe, Stefan H. I.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431720/
https://ncbi.nlm.nih.gov/pubmed/25974076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004855
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