Immunization of Mice with Live-Attenuated Late Liver Stage-Arresting Plasmodium yoelii Parasites Generates Protective Antibody Responses to Preerythrocytic Stages of Malaria

Understanding protective immunity to malaria is essential for the design of an effective vaccine to prevent the large number of infections and deaths caused by this parasitic disease. To date, whole-parasite immunization with attenuated parasites is the most effective method to confer sterile protec...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Keitany, Gladys J., Sack, Brandon, Smithers, Hannah, Chen, Lin, Jang, Ihn K., Sebastian, Leslie, Gupta, Megha, Sather, D. Noah, Vignali, Marissa, Vaughan, Ashley M., Kappe, Stefan H. I., Wang, Ruobing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249261/
https://ncbi.nlm.nih.gov/pubmed/25267837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02320-14
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