Immunization of Mice with Live-Attenuated Late Liver Stage-Arresting Plasmodium yoelii Parasites Generates Protective Antibody Responses to Preerythrocytic Stages of Malaria

Understanding protective immunity to malaria is essential for the design of an effective vaccine to prevent the large number of infections and deaths caused by this parasitic disease. To date, whole-parasite immunization with attenuated parasites is the most effective method to confer sterile protec...

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Enregistré dans:
Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Keitany, Gladys J., Sack, Brandon, Smithers, Hannah, Chen, Lin, Jang, Ihn K., Sebastian, Leslie, Gupta, Megha, Sather, D. Noah, Vignali, Marissa, Vaughan, Ashley M., Kappe, Stefan H. I., Wang, Ruobing
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Microbial Immunity and Vaccines
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249261/
https://ncbi.nlm.nih.gov/pubmed/25267837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02320-14
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