Immunization of Mice with Live-Attenuated Late Liver Stage-Arresting Plasmodium yoelii Parasites Generates Protective Antibody Responses to Preerythrocytic Stages of Malaria

Understanding protective immunity to malaria is essential for the design of an effective vaccine to prevent the large number of infections and deaths caused by this parasitic disease. To date, whole-parasite immunization with attenuated parasites is the most effective method to confer sterile protec...

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Udgivet i:Infect Immun
Main Authors: Keitany, Gladys J., Sack, Brandon, Smithers, Hannah, Chen, Lin, Jang, Ihn K., Sebastian, Leslie, Gupta, Megha, Sather, D. Noah, Vignali, Marissa, Vaughan, Ashley M., Kappe, Stefan H. I., Wang, Ruobing
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249261/
https://ncbi.nlm.nih.gov/pubmed/25267837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02320-14
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