Immunization of Mice with Live-Attenuated Late Liver Stage-Arresting Plasmodium yoelii Parasites Generates Protective Antibody Responses to Preerythrocytic Stages of Malaria

Understanding protective immunity to malaria is essential for the design of an effective vaccine to prevent the large number of infections and deaths caused by this parasitic disease. To date, whole-parasite immunization with attenuated parasites is the most effective method to confer sterile protec...

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Vydáno v:Infect Immun
Hlavní autoři: Keitany, Gladys J., Sack, Brandon, Smithers, Hannah, Chen, Lin, Jang, Ihn K., Sebastian, Leslie, Gupta, Megha, Sather, D. Noah, Vignali, Marissa, Vaughan, Ashley M., Kappe, Stefan H. I., Wang, Ruobing
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249261/
https://ncbi.nlm.nih.gov/pubmed/25267837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02320-14
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