A Plasmodium Parasite with Complete Late Liver Stage Arrest Protects against Preerythrocytic and Erythrocytic Stage Infection in Mice

Genetically attenuated malaria parasites (GAP) that arrest during liver stage development are powerful immunogens and afford complete and durable protection against sporozoite infection. Late liver stage-arresting GAP provide superior protection against sporozoite challenge in mice compared to early...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Vaughan, Ashley M., Sack, Brandon K., Dankwa, Dorender, Minkah, Nana, Nguyen, Thao, Cardamone, Hayley, Kappe, Stefan H. I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913857/
https://ncbi.nlm.nih.gov/pubmed/29440367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00088-18
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