A Plasmodium Parasite with Complete Late Liver Stage Arrest Protects against Preerythrocytic and Erythrocytic Stage Infection in Mice

Genetically attenuated malaria parasites (GAP) that arrest during liver stage development are powerful immunogens and afford complete and durable protection against sporozoite infection. Late liver stage-arresting GAP provide superior protection against sporozoite challenge in mice compared to early...

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Опубликовано в: :Infect Immun
Главные авторы: Vaughan, Ashley M., Sack, Brandon K., Dankwa, Dorender, Minkah, Nana, Nguyen, Thao, Cardamone, Hayley, Kappe, Stefan H. I.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
Предметы:
Microbial Immunity and Vaccines
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913857/
https://ncbi.nlm.nih.gov/pubmed/29440367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00088-18
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