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Mechanisms of Stage-Transcending Protection Following Immunization of Mice with Late Liver Stage-Arresting Genetically Attenuated Malaria Parasites

Malaria, caused by Plasmodium parasite infection, continues to be one of the leading causes of worldwide morbidity and mortality. Development of an effective vaccine has been encumbered by the complex life cycle of the parasite that has distinct pre-erythrocytic and erythrocytic stages of infection...

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Publicat a:PLoS Pathog
Autors principals: Sack, Brandon K., Keitany, Gladys J., Vaughan, Ashley M., Miller, Jessica L., Wang, Ruobing, Kappe, Stefan H. I.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431720/
https://ncbi.nlm.nih.gov/pubmed/25974076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004855
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