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The tryptophan-derived endogenous arylhydrocarbon receptor ligand 6-formylindolo[3,2-b]carbazole (FICZ) is a nanomolar UVA-photosensitizer in epidermal keratinocytes
Endogenous UVA-chromophores may act as sensitizers of oxidative stress underlying cutaneous photoaging and photocarcinogenesis, but the molecular identity of non-DNA key chromophores displaying UVA-driven photodyamic activity in human skin remains largely undefined. Here we report that 6-formylindol...
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Izdano u: | J Invest Dermatol |
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Glavni autori: | , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2014
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4430374/ https://ncbi.nlm.nih.gov/pubmed/25431849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.503 |
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