NQO1-activated Phenothiazinium Redox Cyclers for the Targeted Bioreductive Induction of Cancer Cell Apoptosis

Por Wondrak, Georg T.
Publicado em 2007

Redox-Directed Cancer Therapeutics: Molecular Mechanisms and Opportunities

Por Wondrak, Georg T.
Publicado em 2009

UVA Causes Dual Inactivation of Cathepsin B and L Underlying Lysosomal Dysfunction in Human Dermal Fibroblasts

Por Lamore, Sarah D., Wondrak, Georg T.
Publicado em 2013

Autophagic-lysosomal dysregulation downstream of cathepsin B inactivation in human skin fibroblasts exposed to UVA

Por Lamore, Sarah D., Wondrak, Georg T.
Publicado em 2011

Zinc pyrithione impairs zinc homeostasis and upregulates stress response gene expression in reconstructed human epidermis

Por Lamore, Sarah D., Wondrak, Georg T.
Publicado em 2011

The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in human skin cells

Por Lamore, Sarah D., Cabello, Christopher M., Wondrak, Georg T.
Publicado em 2009

Proteomic Identification of Cathepsin B and Nucleophosmin as Novel UVA-Targets in Human Skin Fibroblasts

Por Lamore, Sarah D., Qiao, Shuxi, Horn, David, Wondrak, Georg T.
Publicado em 2010

The Nrf2-inducers tanshinone I and dihydrotanshinone protect human skin cells and reconstructed human skin against solar simulated UV()

Por Tao, Shasha, Justiniano, Rebecca, Zhang, Donna D., Wondrak, Georg T.
Publicado em 2013

Antimelanoma Activity of the Redox Dye DCPIP (2,6-Dichlorophenolindophenol) is Antagonized by NQO1

Por Cabello, Christopher M., Bair, Warner B., Bause, Alexandra S., Wondrak, Georg T.
Publicado em 2009

GLO1 Overexpression in Human Malignant Melanoma

Por Bair, Warner B, Cabello, Christopher M, Uchida, Koji, Bause, Alexandra S, Wondrak, Georg T
Publicado em 2010

Phenotypic Identification of the Redox Dye Methylene Blue as an Antagonist of Heat Shock Response Gene Expression in Metastatic Melanoma Cells

Por Davis, Angela L., Cabello, Christopher M., Qiao, Shuxi, Azimian, Sara, Wondrak, Georg T.
Publicado em 2013

Nrf2 Modulates Contractile and Metabolic Properties of Skeletal Muscle in Streptozotocin-Induced Diabetic Atrophy

Por Whitman, Samantha A, Long, Min, Wondrak, Georg, Zheng, Hongting, Zhang, Donna D.
Publicado em 2013

D-Penicillamine targets metastatic melanoma cells with induction of the unfolded protein response (UPR) and Noxa (PMAIP1)-dependent mitochondrial apoptosis

Por Qiao, Shuxi, Cabello, Christopher M., Lamore, Sarah D., Lesson, Jessica L., Wondrak, Georg T.
Publicado em 2012

Resveratrol Prevents Epigenetic Silencing of BRCA-1 by the Aromatic Hydrocarbon Receptor in Human Breast Cancer Cells(2)

Por Papoutsis, Andreas J., Lamore, Sarah D., Wondrak, Georg T., Selmin, Ornella I., Romagnolo, Donato F.
Publicado em 2010

The experimental chemotherapeutic N(6)-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A (p21) upregulation in human cancer cell lines

Por Cabello, Christopher M., Bair, Warner B., Ley, Stephanie, Lamore, Sarah D., Azimian, Sara, Wondrak, Georg T.
Publicado em 2008

The tryptophan-derived endogenous arylhydrocarbon receptor ligand 6-formylindolo[3,2-b]carbazole (FICZ) is a nanomolar UVA-photosensitizer in epidermal keratinocytes

Por Park, Sophia L., Justiniano, Rebecca, Williams, Joshua D., Cabello, Christopher M., Qiao, Shuxi, Wondrak, Georg T.
Publicado no J Invest Dermatol (2014)

Systemic administration of the apocarotenoid bixin protects skin against solar UV-induced damage through activation of NRF2

Por Tao, Shasha, Park, Sophia L., de la Vega, Montserrat Rojo, Zhang, Donna D., Wondrak, Georg T.
Publicado no Free Radic Biol Med (2015)

The Cinnamon-derived Michael Acceptor Cinnamic Aldehyde Impairs Melanoma Cell Proliferation, Invasiveness, and Tumor Growth

Por Cabello, Christopher M., Bair, Warner B., Lamore, Sarah D., Ley, Stephanie, Bause, Alexandra S., Azimian, Sara, Wondrak, Georg T.
Publicado em 2008

The Malondialdehyde-derived Fluorophore DHP-lysine is a Potent Sensitizer of UVA-induced Photooxidative Stress in Human Skin Cells

Por Lamore, Sarah D., Azimian, Sara, Horn, David, Anglin, Bobbi L., Uchida, Koji, Cabello, Christopher M., Wondrak, Georg T.
Publicado em 2010

Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy

Por Zheng, Hongting, Whitman, Samantha A., Wu, Wei, Wondrak, Georg T., Wong, Pak K., Fang, Deyu, Zhang, Donna D.
Publicado em 2011