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Resveratrol Prevents Epigenetic Silencing of BRCA-1 by the Aromatic Hydrocarbon Receptor in Human Breast Cancer Cells(2)

The BRCA-1 protein is a tumor suppressor involved in repair of DNA damage. Epigenetic mechanisms contribute to its reduced expression in sporadic breast tumors. Through diet, humans are exposed to a complex mixture of xenobiotics and natural ligands of the aromatic hydrocarbon receptor (AhR), which...

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Main Authors: Papoutsis, Andreas J., Lamore, Sarah D., Wondrak, Georg T., Selmin, Ornella I., Romagnolo, Donato F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Nutrition 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139234/
https://ncbi.nlm.nih.gov/pubmed/20631324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.110.123422
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