Genistein Prevents BRCA1 CpG Methylation and Proliferation in Human Breast Cancer Cells with Activated Aromatic Hydrocarbon Receptor

Background: Previous studies have suggested a causative role for agonists of the aromatic hydrocarbon receptor (AhR) in the etiology of breast cancer 1, early-onset (BRCA-1)–silenced breast tumors, for which prospects for treatment remain poor. Objectives: We investigated the regulation of BRCA1 by...

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Опубликовано в: :Curr Dev Nutr
Главные авторы: Romagnolo, Donato F, Donovan, Micah G, Papoutsis, Andreas J, Doetschman, Tom C, Selmin, Ornella I
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2017
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998349/
https://ncbi.nlm.nih.gov/pubmed/29955703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/cdn.117.000562
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