Induction of long interspersed nucleotide element-1 (L1) retrotransposition by 6-formylindolo[3,2-b]carbazole (FICZ), a tryptophan photoproduct

Long interspersed nucleotide element-1 (L1) is a retroelement comprising about 17% of the human genome, of which 80–100 copies are competent as mobile elements (retrotransposition: L1-RTP). Although the genetic structures modified during L1-RTP have been clarified, little is known about the cellular...

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Main Authors: Okudaira, Noriyuki, Iijima, Kenta, Koyama, Takayoshi, Minemoto, Yuzuru, Kano, Shigeyuki, Mimori, Akio, Ishizaka, Yukihito
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973001/
https://ncbi.nlm.nih.gov/pubmed/20852066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001252107
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