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Retrotransposition of Long Interspersed Element 1 Induced by Methamphetamine or Cocaine
Long interspersed element 1 (L1) is a retroelement constituting ∼17% of the human genome. A single human cell has 80–100 copies of L1 capable of retrotransposition (L1-RTP), ∼10% of which are “hot L1” copies, meaning they are primed for “jumping” within the genome. Recent studies demonstrated induct...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162154/ https://ncbi.nlm.nih.gov/pubmed/25053411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.559419 |
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