The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish

The tryptophan photooxidation product 6-formylindolo[3,2-b]carbazole (FICZ) has been proposed as a physiological ligand for the mammalian aryl hydrocarbon receptor (AHR), which it binds with high affinity, inducing expression of cytochrome P450 1A1 (CYP1A1). We investigated whether the response to F...

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Detalhes bibliográficos
Main Authors: Jönsson, Maria E., Franks, Diana G., Woodin, Bruce R., Jenny, Matthew J., Garrick, Rita A., Behrendt, Lars, Hahn, Mark E., Stegeman, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838191/
https://ncbi.nlm.nih.gov/pubmed/19615353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2009.07.003
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