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MicroRNA-103-1 Selectively Downregulates Brain NCX1 and Its Inhibition by Anti-miRNA Ameliorates Stroke Damage and Neurological Deficits

Na(+)/Ca2+ exchanger (NCX) is a plasma membrane transporter that, by regulating Ca2+ and Na(+) homeostasis, contributes to brain stroke damage. The objectives of this study were to investigate whether there might be miRNAs in the brain able to regulate NCX1 expression and, thereafter, to set up a va...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther
Egile Nagusiak: Vinciguerra, Antonio, Formisano, Luigi, Cerullo, Pierpaolo, Guida, Natascia, Cuomo, Ornella, Esposito, Alba, Di Renzo, Gianfranco, Annunziato, Lucio, Pignataro, Giuseppe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428397/
https://ncbi.nlm.nih.gov/pubmed/24954474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.113
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