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MicroRNA-103-1 Selectively Downregulates Brain NCX1 and Its Inhibition by Anti-miRNA Ameliorates Stroke Damage and Neurological Deficits

Na(+)/Ca2+ exchanger (NCX) is a plasma membrane transporter that, by regulating Ca2+ and Na(+) homeostasis, contributes to brain stroke damage. The objectives of this study were to investigate whether there might be miRNAs in the brain able to regulate NCX1 expression and, thereafter, to set up a va...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Mol Ther
Κύριοι συγγραφείς: Vinciguerra, Antonio, Formisano, Luigi, Cerullo, Pierpaolo, Guida, Natascia, Cuomo, Ornella, Esposito, Alba, Di Renzo, Gianfranco, Annunziato, Lucio, Pignataro, Giuseppe
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428397/
https://ncbi.nlm.nih.gov/pubmed/24954474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.113
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