MicroRNA-103-1 Selectively Downregulates Brain NCX1 and Its Inhibition by Anti-miRNA Ameliorates Stroke Damage and Neurological Deficits

Na(+)/Ca2+ exchanger (NCX) is a plasma membrane transporter that, by regulating Ca2+ and Na(+) homeostasis, contributes to brain stroke damage. The objectives of this study were to investigate whether there might be miRNAs in the brain able to regulate NCX1 expression and, thereafter, to set up a va...

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Библиографические подробности
Опубликовано в: :Mol Ther
Главные авторы: Vinciguerra, Antonio, Formisano, Luigi, Cerullo, Pierpaolo, Guida, Natascia, Cuomo, Ornella, Esposito, Alba, Di Renzo, Gianfranco, Annunziato, Lucio, Pignataro, Giuseppe
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428397/
https://ncbi.nlm.nih.gov/pubmed/24954474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.113
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