MicroRNA-103-1 Selectively Downregulates Brain NCX1 and Its Inhibition by Anti-miRNA Ameliorates Stroke Damage and Neurological Deficits

Na(+)/Ca2+ exchanger (NCX) is a plasma membrane transporter that, by regulating Ca2+ and Na(+) homeostasis, contributes to brain stroke damage. The objectives of this study were to investigate whether there might be miRNAs in the brain able to regulate NCX1 expression and, thereafter, to set up a va...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Vinciguerra, Antonio, Formisano, Luigi, Cerullo, Pierpaolo, Guida, Natascia, Cuomo, Ornella, Esposito, Alba, Di Renzo, Gianfranco, Annunziato, Lucio, Pignataro, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428397/
https://ncbi.nlm.nih.gov/pubmed/24954474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.113
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