Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy

Mammalian target of rapamycin (mTOR) is a key protein kinase that regulates cell growth, metabolism, and autophagy to maintain cellular homeostasis. Its activity is inhibited by adverse conditions, including nutrient limitation, hypoxia, and DNA damage. In this study, we demonstrate that Che-1, a RN...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:EMBO J
Main Authors: Desantis, Agata, Bruno, Tiziana, Catena, Valeria, De Nicola, Francesca, Goeman, Frauke, Iezzi, Simona, Sorino, Cristina, Ponzoni, Maurilio, Bossi, Gianluca, Federico, Vincenzo, La Rosa, Francesca, Ricciardi, Maria Rosaria, Lesma, Elena, De Meo, Paolo D'Onorio, Castrignanò, Tiziana, Petrucci, Maria Teresa, Pisani, Francesco, Chesi, Marta, Bergsagel, P Leif, Floridi, Aristide, Tonon, Giovanni, Passananti, Claudio, Blandino, Giovanni, Fanciulli, Maurizio
פורמט: Artigo
שפה:Inglês
יצא לאור: BlackWell Publishing Ltd 2015
נושאים:
Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426481/
https://ncbi.nlm.nih.gov/pubmed/25770584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489920
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים