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SHAPE Selection (SHAPES) enrich for RNA structure signal in SHAPE sequencing-based probing data

Selective 2′ Hydroxyl Acylation analyzed by Primer Extension (SHAPE) is an accurate method for probing of RNA secondary structure. In existing SHAPE methods, the SHAPE probing signal is normalized to a no-reagent control to correct for the background caused by premature termination of the reverse tr...

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Bibliografske podrobnosti
izdano v:RNA
Main Authors: Poulsen, Line Dahl, Kielpinski, Lukasz Jan, Salama, Sofie R., Krogh, Anders, Vinther, Jeppe
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408784/
https://ncbi.nlm.nih.gov/pubmed/25805860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.047068.114
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