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SHAPE Selection (SHAPES) enrich for RNA structure signal in SHAPE sequencing-based probing data

Selective 2′ Hydroxyl Acylation analyzed by Primer Extension (SHAPE) is an accurate method for probing of RNA secondary structure. In existing SHAPE methods, the SHAPE probing signal is normalized to a no-reagent control to correct for the background caused by premature termination of the reverse tr...

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Библиографические подробности
Опубликовано в: :RNA
Главные авторы: Poulsen, Line Dahl, Kielpinski, Lukasz Jan, Salama, Sofie R., Krogh, Anders, Vinther, Jeppe
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408784/
https://ncbi.nlm.nih.gov/pubmed/25805860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.047068.114
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