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SHAPE Selection (SHAPES) enrich for RNA structure signal in SHAPE sequencing-based probing data

Selective 2′ Hydroxyl Acylation analyzed by Primer Extension (SHAPE) is an accurate method for probing of RNA secondary structure. In existing SHAPE methods, the SHAPE probing signal is normalized to a no-reagent control to correct for the background caused by premature termination of the reverse tr...

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Dettagli Bibliografici
Pubblicato in:RNA
Autori principali: Poulsen, Line Dahl, Kielpinski, Lukasz Jan, Salama, Sofie R., Krogh, Anders, Vinther, Jeppe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408784/
https://ncbi.nlm.nih.gov/pubmed/25805860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.047068.114
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