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RNase H sequence preferences influence antisense oligonucleotide efficiency

RNase H cleaves RNA in RNA–DNA duplexes. It is present in all domains of life as well as in multiple viruses and is essential for mammalian development and for human immunodeficiency virus replication. Here, we developed a sequencing-based method to measure the cleavage of thousands of different RNA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Kiełpiński, Łukasz J., Hagedorn, Peter H., Lindow, Morten, Vinther, Jeppe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728404/
https://ncbi.nlm.nih.gov/pubmed/29126318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1073
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