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RNase H sequence preferences influence antisense oligonucleotide efficiency
RNase H cleaves RNA in RNA–DNA duplexes. It is present in all domains of life as well as in multiple viruses and is essential for mammalian development and for human immunodeficiency virus replication. Here, we developed a sequencing-based method to measure the cleavage of thousands of different RNA...
Shranjeno v:
| izdano v: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728404/ https://ncbi.nlm.nih.gov/pubmed/29126318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1073 |
| Oznake: |
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