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SHAPE Selection (SHAPES) enrich for RNA structure signal in SHAPE sequencing-based probing data

Selective 2′ Hydroxyl Acylation analyzed by Primer Extension (SHAPE) is an accurate method for probing of RNA secondary structure. In existing SHAPE methods, the SHAPE probing signal is normalized to a no-reagent control to correct for the background caused by premature termination of the reverse tr...

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Dades bibliogràfiques
Publicat a:RNA
Autors principals: Poulsen, Line Dahl, Kielpinski, Lukasz Jan, Salama, Sofie R., Krogh, Anders, Vinther, Jeppe
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408784/
https://ncbi.nlm.nih.gov/pubmed/25805860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.047068.114
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