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TNF Superfamily Protein–Protein Interactions: Feasibility of Small-Molecule Modulation
The tumor necrosis factor (TNF) superfamily (TNFSF) contains about thirty structurally related receptors (TNFSFRs) and about twenty protein ligands that bind to one or more of these receptors. Almost all of these cell surface protein-protein interactions (PPIs) represent high-value therapeutic targe...
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| Udgivet i: | Curr Drug Targets |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408546/ https://ncbi.nlm.nih.gov/pubmed/25706111 |
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