Chargement en cours...

Toward Small-Molecule Inhibition of Protein–Protein Interactions: General Aspects and Recent Progress in Targeting Costimulatory and Coinhibitory (Immune Checkpoint) Interactions

Protein-protein interactions (PPIs) that are part of the costimulatory and coinhibitory (immune checkpoint) signaling are critical for adequate T cell response and are important therapeutic targets for immunomodulation. Biologics targeting them have already achieved considerable clinical success in...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Curr Top Med Chem
Auteurs principaux: Bojadzic, Damir, Buchwald, Peter
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067980/
https://ncbi.nlm.nih.gov/pubmed/29848279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1568026618666180531092503
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!