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Small-molecule inhibitors of protein-protein interactions: progressing towards the reality
The past twenty years have seen many advances in our understanding of protein-protein interactions (PPI) and how to target them with small-molecule therapeutics. In 2004, we reviewed some early successes; since then, potent inhibitors have been developed for diverse protein complexes, and compounds...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4179228/ https://ncbi.nlm.nih.gov/pubmed/25237857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.09.001 |
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