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Structural and Enzymatic Insights into Caspase-2 Protein Substrate Recognition and Catalysis
Caspase-2, the most evolutionarily conserved member in the human caspase family, may play important roles in stress-induced apoptosis, cell cycle regulation, and tumor suppression. In biochemical assays, caspase-2 uniquely prefers a pentapeptide (such as VDVAD) rather than a tetrapeptide, as require...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190824/ https://ncbi.nlm.nih.gov/pubmed/21828056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.247627 |
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