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Structural basis of substrate recognition and catalysis by fucosyltransferase 8

Fucosylation of the innermost GlcNAc of N-glycans by fucosyltransferase 8 (FUT8) is an important step in the maturation of complex and hybrid N-glycans. This simple modification can dramatically affect the activities and half-lives of glycoproteins, effects that are relevant to understanding the inv...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Järvå, Michael A., Dramicanin, Marija, Lingford, James P., Mao, Runyu, John, Alan, Jarman, Kate E., Grinter, Rhys, Goddard-Borger, Ethan D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212660/
https://ncbi.nlm.nih.gov/pubmed/32220931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013291
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