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Targeting epigenetic protein–protein interactions with small-molecule inhibitors

Epigenetic protein–protein interactions (PPIs) play essential roles in regulating gene expression, and their dysregulations have been implicated in many diseases. These PPIs are comprised of reader domains recognizing post-translational modifications on histone proteins, and of scaffolding proteins...

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Bibliografiske detaljer
Udgivet i:Future Med Chem
Main Authors: Linhares, Brian M, Grembecka, Jolanta, Cierpicki, Tomasz
Format: Artigo
Sprog:Inglês
Udgivet: Newlands Press Ltd 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7421387/
https://ncbi.nlm.nih.gov/pubmed/32551894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2020-0082
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