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Small-Molecule Inhibitors of the CD40–CD40L Costimulatory Protein-Protein Interaction
Costimulatory interactions are required for T cell activation and development of an effective immune response; hence, they are valuable therapeutic targets for immunomodulation. However, they, as all other protein-protein interactions, are difficult to target by small molecules. Here, we report the...
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| Publicado no: | J Med Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5823691/ https://ncbi.nlm.nih.gov/pubmed/29024591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.7b01154 |
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