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TNF Superfamily Protein–Protein Interactions: Feasibility of Small-Molecule Modulation

The tumor necrosis factor (TNF) superfamily (TNFSF) contains about thirty structurally related receptors (TNFSFRs) and about twenty protein ligands that bind to one or more of these receptors. Almost all of these cell surface protein-protein interactions (PPIs) represent high-value therapeutic targe...

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Bibliografische gegevens
Gepubliceerd in:Curr Drug Targets
Hoofdauteurs: Song, Yun, Buchwald, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408546/
https://ncbi.nlm.nih.gov/pubmed/25706111
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