Decitabine priming enhances the antileukemic effects of exportin 1 (XPO1) selective inhibitor selinexor in acute myeloid leukemia

The prognosis of acute myeloid leukemia (AML) is poor, highlighting the need for novel treatments. Hypomethylating agents, including decitabine are used to treat elderly AML patients with relative success. Targeting nuclear export receptor (exportin 1 [XPO1]) is a novel approach to restore tumor sup...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood
Main Authors: Ranganathan, Parvathi, Yu, Xueyan, Santhanam, Ramasamy, Hofstetter, Jessica, Walker, Alison, Walsh, Katherine, Bhatnagar, Bhavana, Klisovic, Rebecca, Vasu, Sumithira, Phelps, Mitch A., Devine, Steven, Shacham, Sharon, Kauffman, Michael, Marcucci, Guido, Blum, William, Garzon, Ramiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408293/
https://ncbi.nlm.nih.gov/pubmed/25716206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-607648
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados