Selinexor in Combination with Decitabine in Patients with Acute Myeloid Leukemia: Results from a Phase 1 study

Current treatment options for older and relapsed or refractory (R/R) acute myeloid leukemia (AML) patients are limited and represent an unmet need. Based on preclinical studies showing strong anti-leukemic effects in vivo, this phase I dose-escalation study assessed the safety and preliminary clinic...

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Publicado en:Leuk Lymphoma
Main Authors: Bhatnagar, Bhavana, Zhao, Qiuhong, Mims, Alice S., Vasu, Sumithira, Behbehani, Gregory K., Larkin, Karilyn, Blachly, James S., Blum, William, Klisovic, Rebecca B., Ruppert, Amy S., Orwick, Shelley, Oakes, Christopher, Ranganathan, Parvathi, Byrd, John C., Walker, Alison R., Garzon, Ramiro
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552944/
https://ncbi.nlm.nih.gov/pubmed/31545113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2019.1665664
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