Selinexor in Combination with Decitabine in Patients with Acute Myeloid Leukemia: Results from a Phase 1 study

Current treatment options for older and relapsed or refractory (R/R) acute myeloid leukemia (AML) patients are limited and represent an unmet need. Based on preclinical studies showing strong anti-leukemic effects in vivo, this phase I dose-escalation study assessed the safety and preliminary clinic...

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Pubblicato in:Leuk Lymphoma
Autori principali: Bhatnagar, Bhavana, Zhao, Qiuhong, Mims, Alice S., Vasu, Sumithira, Behbehani, Gregory K., Larkin, Karilyn, Blachly, James S., Blum, William, Klisovic, Rebecca B., Ruppert, Amy S., Orwick, Shelley, Oakes, Christopher, Ranganathan, Parvathi, Byrd, John C., Walker, Alison R., Garzon, Ramiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552944/
https://ncbi.nlm.nih.gov/pubmed/31545113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2019.1665664
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