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A Novel Method for Analyzing Extremely Biased Agonism at G Protein–Coupled Receptors

Seven transmembrane receptors were originally named and characterized based on their ability to couple to heterotrimeric G proteins. The assortment of coupling partners for G protein–coupled receptors has subsequently expanded to include other effectors (most notably the βarrestins). This diversity...

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Pubblicato in:Mol Pharmacol
Autori principali: Stahl, Edward L., Zhou, Lei, Ehlert, Frederick J., Bohn, Laura M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407734/
https://ncbi.nlm.nih.gov/pubmed/25680753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.096503
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