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Posttranslation Modification of G Protein-Coupled Receptor in Relationship to Biased Agonism
Biased signaling has been reported with a series of G protein-coupled receptors (GPCRs), including β(2)-adrenergic receptor and μ-opioid receptor (OPRM1). The concept of biased signaling suggests that the agonists of one particular receptor may activate the downstream signaling pathways with differe...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3833076/ https://ncbi.nlm.nih.gov/pubmed/23374194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-407865-9.00018-2 |
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