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A Practical Guide to Approaching Biased Agonism at G Protein Coupled Receptors
Biased agonism, the ability of a receptor to differentially activate downstream signaling pathways depending on binding of a “biased” agonist compared to a “balanced” agonist, is a well-established paradigm for G protein-coupled receptor (GPCR) signaling. Biased agonists have the promise to act as s...
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| Publié dans: | Front Neurosci |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5258729/ https://ncbi.nlm.nih.gov/pubmed/28174517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00017 |
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