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Biased agonists of the chemokine receptor CXCR3 differentially control chemotaxis and inflammation

The chemokine receptor CXCR3 plays a central role in inflammation by mediating effector/memory T cell migration in various diseases; however, drugs targeting CXCR3 and other chemokine receptors are largely ineffective in treating inflammation. Chemokines, the endogenous peptide ligands of chemokine...

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Dades bibliogràfiques
Publicat a:Sci Signal
Autors principals: Smith, Jeffrey S., Nicholson, Lowell T., Suwanpradid, Jutamas, Glenn, Rachel A., Knape, Nicole M., Alagesan, Priya, Gundry, Jaimee N., Wehrman, Thomas S., Reck Atwater, Amber, Gunn, Michael D., MacLeod, Amanda S., Rajagopal, Sudarshan
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329291/
https://ncbi.nlm.nih.gov/pubmed/30401786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaq1075
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