Pseudomonas aeruginosa Pyocyanin Induces Neutrophil Death via Mitochondrial Reactive Oxygen Species and Mitochondrial Acid Sphingomyelinase

Aims: Pulmonary infections with Pseudomonas aeruginosa are a serious clinical problem and are often lethal. Because many strains of P. aeruginosa are resistant to antibiotics, therapeutic options are limited. Neutrophils play an important role in the host's early acute defense against pulmonary...

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Dettagli Bibliografici
Pubblicato in:Antioxid Redox Signal
Autori principali: Managò, Antonella, Becker, Katrin Anne, Carpinteiro, Alexander, Wilker, Barbara, Soddemann, Matthias, Seitz, Aaron P., Edwards, Michael J., Grassmé, Heike, Szabò, Ildiko, Gulbins, Erich
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2015
Soggetti:
Forum Original Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403017/
https://ncbi.nlm.nih.gov/pubmed/25686490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.5979
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