Regulation of hematogenous tumor metastasis by acid sphingomyelinase

Metastatic dissemination of cancer cells is the ultimate hallmark of malignancy and accounts for approximately 90% of human cancer deaths. We investigated the role of acid sphingomyelinase (Asm) in the hematogenous metastasis of melanoma cells. Intravenous injection of B16F10 melanoma cells into wil...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Carpinteiro, Alexander, Becker, Katrin Anne, Japtok, Lukasz, Hessler, Gabriele, Keitsch, Simone, Požgajovà, Miroslava, Schmid, Kurt W, Adams, Constantin, Müller, Stefan, Kleuser, Burkhard, Edwards, Michael J, Grassmé, Heike, Helfrich, Iris, Gulbins, Erich
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459814/
https://ncbi.nlm.nih.gov/pubmed/25851537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404571
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