Pseudomonas aeruginosa Pyocyanin Induces Neutrophil Death via Mitochondrial Reactive Oxygen Species and Mitochondrial Acid Sphingomyelinase

Aims: Pulmonary infections with Pseudomonas aeruginosa are a serious clinical problem and are often lethal. Because many strains of P. aeruginosa are resistant to antibiotics, therapeutic options are limited. Neutrophils play an important role in the host's early acute defense against pulmonary...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Managò, Antonella, Becker, Katrin Anne, Carpinteiro, Alexander, Wilker, Barbara, Soddemann, Matthias, Seitz, Aaron P., Edwards, Michael J., Grassmé, Heike, Szabò, Ildiko, Gulbins, Erich
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
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Forum Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403017/
https://ncbi.nlm.nih.gov/pubmed/25686490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.5979
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