Staphylococcus aureus Alpha-Toxin Disrupts Endothelial-Cell Tight Junctions via Acid Sphingomyelinase and Ceramide

Staphylococcus aureus (S. aureus) infections are among the most common and severe infections, garnering notoriety in an era of increasing resistance to antibiotics. It is therefore important to define molecular mechanisms by which this pathogen attacks host cells. Here, we demonstrate that alpha-tox...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Becker, Katrin Anne, Fahsel, Björn, Kemper, Hannes, Mayeres, Joelina, Li, Cao, Wilker, Barbara, Keitsch, Simone, Soddemann, Matthias, Sehl, Carolin, Kohnen, Marcus, Edwards, Michael J., Grassmé, Heike, Caldwell, Charles C., Seitz, Aaron, Fraunholz, Martin, Gulbins, Erich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736828/
https://ncbi.nlm.nih.gov/pubmed/29084896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00606-17
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